Description

3-Bromo-6-Chloro-5-Iodopyrazin-2-Amine is a high-purity, multi-halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex heterocyclic scaffolds. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Used in the creation of specialized organic electronic materials and ligands for catalytic systems.
• Chemical Biology Probes: Serves as a starting material for synthesizing molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring halogenated pyrazine cores.

Basic Information

Product Name	3-Bromo-6-Chloro-5-Iodopyrazin-2-Amine
CAS No.	1251941-18-0
Molecular Formula	C4H2BrClIN3
Molecular Weight	358.34 g/mol
Synonyms	2-Amino-3-bromo-6-chloro-5-iodopyrazine; 5-Iodo-3-bromo-6-chloropyrazin-2-amine; 3-Bromo-6-chloro-5-iodo-2-pyrazinamine; 2-Pyrazinamine, 3-bromo-6-chloro-5-iodo-; 1251941-18-0; Bromochloroiodopyrazinamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloro-5-Iodopyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.