Description

(6-Amino-5-Chloro-Pyridin-3-Yl)-Methanol is a high-purity pyridine derivative building block of significant importance in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both an amino and a hydroxymethyl group on a chlorinated pyridine core, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its modifiable pyridine scaffold.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and R&D Laboratories: Utilized in fundamental research to explore new chemical reactions and develop novel synthetic methodologies.

Basic Information

Product Name	(6-Amino-5-Chloro-Pyridin-3-Yl)-Methanol
CAS No.	1251924-45-4
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	5-Chloro-6-aminopyridin-3-ylmethanol; 3-Pyridinemethanol, 6-amino-5-chloro-; (6-Amino-5-chloro-3-pyridinyl)methanol; 5-Chloro-6-amino-3-pyridinemethanol; 5-Chloro-6-aminonicotinyl alcohol; 3-(Hydroxymethyl)-5-chloro-6-aminopyridine; 6-Amino-5-chloro-3-pyridylmethanol
EINECS	Contact for details

Quality Control

Our (6-Amino-5-Chloro-Pyridin-3-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.