Description

4-(1-Piperazinyl)-2-Butenoic Acid is a high-purity, specialized piperazine derivative with significant potential in advanced organic synthesis. This compound serves as a versatile and valuable pharmaceutical intermediate and building block for the development of novel active molecules. It is primarily sought by research institutions and chemical manufacturers engaged in the creation of new therapeutic agents, particularly within medicinal chemistry and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) for high-throughput screening and lead optimization.
• Bioconjugation & Linker Chemistry: The carboxylic acid and piperazine functionalities make it suitable for creating custom linkers in antibody-drug conjugates (ADCs) or other bioconjugation applications.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and pesticides.
• Fine Chemical Production: Serves as a precursor for other complex, high-value specialty chemicals.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	4-(1-Piperazinyl)-2-Butenoic Acid
CAS No.	1251504-25-2
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	2-Butenoic acid, 4-(1-piperazinyl)-; 4-Piperazin-1-ylbut-2-enoic acid; (E)-4-(Piperazin-1-yl)but-2-enoic acid; 4-(Piperazin-1-yl)but-2-enoic acid; 1-Piperazinebut-2-enoic acid; 4-Piperazin-1-yl-2-butenoic acid; 4-(1-Piperazinyl)-2-butenoic Acid
EINECS	Contact for details

Quality Control

Our 4-(1-Piperazinyl)-2-Butenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.