Description

3,4,6,7-Tetrahydro-[1,2,3]Triazolo[4,5-C]Pyridine-5-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyridine heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular scaffolds with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of specialized probes for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	3,4,6,7-Tetrahydro-[1,2,3]Triazolo[4,5-C]Pyridine-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1251016-63-3
Molecular Formula	C11H16N4O2
Molecular Weight	236.27 g/mol
Synonyms	tert-Butyl 3,4,6,7-tetrahydro-[1,2,3]triazolo[4,5-c]pyridine-5-carboxylate; 5-(tert-Butoxycarbonyl)-3,4,6,7-tetrahydro-[1,2,3]triazolo[4,5-c]pyridine; 1,2,3-Triazolo[4,5-c]pyridine-5-carboxylic acid, 3,4,6,7-tetrahydro-, 1,1-dimethylethyl ester; BOC-protected triazolopyridine; Triazolopyridine tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 3,4,6,7-Tetrahydro-[1,2,3]Triazolo[4,5-C]Pyridine-5-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.