Description

3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine-6-Carboxylic Acid tert-Butyl Ester is a high-value, heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily sought after by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of active pharmaceutical ingredients (APIs) for its role in constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with fused pyridopyridazine scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of target compounds for clients.
• Library Synthesis: Valuable for generating diverse chemical libraries for high-throughput screening in early-stage drug discovery.
• API Development: Serves as an intermediate in the development and scale-up processes for new active pharmaceutical ingredients.
• Chemical Biology Probes: Can be utilized to create tool compounds for investigating biological mechanisms and target validation.

Basic Information

Item	Detail
Product Name	3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1251015-71-0
Molecular Formula	C13H16ClN3O2
Molecular Weight	281.74 g/mol
Synonyms	tert-Butyl 3-chloro-7,8-dihydro-5H-pyrido[4,3-c]pyridazine-6-carboxylate; 3-Chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine-6-carboxylic acid tert-butyl ester; 6-(tert-Butoxycarbonyl)-3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine; 3-Chloro-6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine; 1251015-71-0; BOC-protected 3-chlorotetrahydropyridopyridazine
EINECS	Contact for details

Quality Control

Our 3-Chloro-7,8-Dihydro-5H-Pyrido[4,3-C]Pyridazine-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards expected by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.