Description

3-Iodo-1,5,6,7-Tetrahydro-Pyrazolo[4,3-B]Pyridine-4-Carboxylic Acid tert-Butyl Ester is a high-value, heterocyclic building block designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists seeking to introduce iodine functionality into complex pyrazolopyridine scaffolds, enabling targeted molecular modifications and structure-activity relationship (SAR) studies. It is primarily utilized in the synthesis of novel active pharmaceutical ingredients (APIs) and discovery libraries within the pharmaceutical, biotechnology, and agrochemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex heterocyclic cores in lead optimization and SAR studies.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes for biological target identification and validation.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and pesticides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Iodo-1,5,6,7-Tetrahydro-Pyrazolo[4,3-B]Pyridine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	1251014-79-5
Molecular Formula	C11H14IN3O2
Molecular Weight	347.15 g/mol
Synonyms	tert-Butyl 3-iodo-1,5,6,7-tetrahydro-4H-pyrazolo[4,3-b]pyridine-4-carboxylate; 3-Iodo-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester; 1,5,6,7-Tetrahydro-3-iodo-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester; 3-Iodo-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-b]pyridine-4-carboxylic acid tert-butyl ester; 1251014-79-5; CAS 1251014-79-5
EINECS	Contact for details

Quality Control

Our 3-Iodo-1,5,6,7-Tetrahydro-Pyrazolo[4,3-B]Pyridine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.