Description

1-Hydroxymethyl-5,6-Dihydro-8H-Imidazo[1,5-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester (Wx140105) is a high-purity, advanced pharmaceutical intermediate characterized by its complex imidazopyrazine heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where its precise chemical functionality enables complex molecular transformations.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• API Synthesis: Used as a building block for constructing the core scaffold or specific side chains of novel Active Pharmaceutical Ingredients (APIs) under development.
• Medicinal Chemistry Research: Employed in research laboratories for structure-activity relationship (SAR) studies and the exploration of new chemical entities (NCEs) with potential biological activity.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the efficient, scalable production of target drug substances.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations that require high-quality, reliable intermediates for custom synthesis projects.
• Chemical Reference Standard: Can be provided as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	1-Hydroxymethyl-5,6-Dihydro-8H-Imidazo[1,5-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester (Wx140105)
CAS No.	1251014-63-7
Molecular Formula	C13H19N3O3
Molecular Weight	265.31 g/mol
Synonyms	tert-Butyl 1-(hydroxymethyl)-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylate; WX-140105; Wx140105; 1-(Hydroxymethyl)-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid 1,1-dimethylethyl ester; 8H-Imidazo[1,5-a]pyrazine-7-carboxylic acid, 5,6-dihydro-1-(hydroxymethyl)-, 1,1-dimethylethyl ester; 1-Hydroxymethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Hydroxymethyl-5,6-Dihydro-8H-Imidazo[1,5-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support our clients' regulatory needs and can supply material suitable for use in GMP-compliant development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). As a specialty organic intermediate, it should be kept under an inert atmosphere if long-term storage is required to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.