Description

tert-Butyl 3-(Hydroxymethyl)-6,7-Dihydroisoxazolo[4,5-C]Pyridine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex fused isoxazolopyridine core. This compound is of significant commercial value as a critical building block in the synthesis of novel, small-molecule drug candidates, particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target APIs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Integrated into multi-step synthesis sequences for the final production of approved or investigational drugs.
• Contract Research & Manufacturing (CRAM) Services: Supplied to organizations specializing in custom synthesis and development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and reaction methodologies.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-(Hydroxymethyl)-6,7-Dihydroisoxazolo[4,5-C]Pyridine-5(4H)-Carboxylate
CAS No.	1251014-58-0
Molecular Formula	C13H20N2O4
Molecular Weight	268.31 g/mol
Synonyms	5(4H)-Isoxazolo[4,5-c]pyridine-5-carboxylic acid, 6,7-dihydro-3-(hydroxymethyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 6,7-dihydro-3-(hydroxymethyl)-5(4H)-isoxazolo[4,5-c]pyridine-5-carboxylate; tert-Butyl 3-(hydroxymethyl)-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-5-carboxylate; BOC-protected isoxazolopyridine intermediate; CAS 1251014-58-0
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(Hydroxymethyl)-6,7-Dihydroisoxazolo[4,5-C]Pyridine-5(4H)-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.