Description

2-Bromo-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), leveraging its reactive bromine and protected carboxylic acid functional groups.
• Chemical Biology Probes: Serves as a starting material for creating specialized molecular probes used to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	2-Bromo-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester
CAS No.	1250999-20-2
Molecular Formula	C11H14BrN3O2
Molecular Weight	300.15 g/mol
Synonyms	tert-Butyl 2-bromo-5,6-dihydro-8H-imidazo[1,2-a]pyrazine-7-carboxylate; 2-Bromo-5,6-dihydro-8H-imidazo[1,2-a]pyrazine-7-carboxylic acid 1,1-dimethylethyl ester; 2-Bromo-8H-imidazo[1,2-a]pyrazine-7-carboxylic acid tert-butyl ester; 1250999-20-2; CAS 1250999-20-2
EINECS	Contact for details

Quality Control

Our 2-Bromo-5,6-Dihydro-8H-Imidazo[1,2-A]Pyrazine-7-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. All batches are analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.