Description

cis-3-Boc-3,7-Diazabicyclo[4.2.0]Octane is a high-value, advanced pharmaceutical intermediate featuring a unique fused bicyclic diazepane scaffold. This compound is critical for medicinal chemistry research and development, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries to create potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the construction of complex drug molecules, particularly in CNS-active compounds.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the diazabicyclo[4.2.0]octane core.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route scouting for Active Pharmaceutical Ingredient (API) synthesis.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against novel biological targets.
• Proteolysis Targeting Chimera (PROTAC) Development: The rigid, three-dimensional structure and amine functionality make it a potential component for linker design in bifunctional degrader molecules.
• Chemical Biology Probes: Useful for creating tool compounds to study enzyme function or protein-protein interactions.

Basic Information

Product Name	cis-3-Boc-3,7-Diazabicyclo[4.2.0]Octane
CAS No.	1250993-51-1
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	cis-3-(tert-Butoxycarbonyl)-3,7-diazabicyclo[4.2.0]octane; (3S,7S)-3-[(tert-Butoxy)carbonyl]-3,7-diazabicyclo[4.2.0]octane; (3R,7R)-3-[(tert-Butoxy)carbonyl]-3,7-diazabicyclo[4.2.0]octane; tert-Butyl cis-3,7-diazabicyclo[4.2.0]octane-3-carboxylate; Boc-Protected cis-3,7-Diazabicyclo[4.2.0]octane; cis-Boc-DABCO Derivative; Bicyclic Diazepane Boc-Protected Amine
EINECS	Contact for details

Quality Control

Our cis-3-Boc-3,7-Diazabicyclo[4.2.0]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.