Description

2-(m-Tolylthio)-6-Chloropyrazine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazine core functionalized with chlorophenyl and tolylthio groups enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing more complex nitrogen-containing heterocycles.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-(m-Tolylthio)-6-Chloropyrazine
CAS No.	1250989-41-3
Molecular Formula	C11H9ClN2S
Molecular Weight	236.72 g/mol
Synonyms	6-Chloro-2-[(3-methylphenyl)thio]pyrazine; 2-(3-Methylphenylthio)-6-chloropyrazine; 2-(m-Tolylmercapto)-6-chloropyrazine; 6-Chloro-2-(3-tolylthio)pyrazine; 2-(3-Methylbenzenethiolato)-6-chloropyrazine; 1250989-41-3; 2-(m-Tolylsulfanyl)-6-chloropyrazine
EINECS	Contact for details

Quality Control

Our 2-(m-Tolylthio)-6-Chloropyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.