Description

2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-B]Pyridine-3-Carbonitrile is a high-value, heterocyclic organic compound serving as a critical synthetic intermediate in advanced chemical synthesis. Its unique fused pyranopyridine structure makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a precursor for the synthesis of specialized ligands, catalysts, and organic electronic materials.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Essential reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-B]Pyridine-3-Carbonitrile
CAS No.	1250840-53-9
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	2-Chloro-5H,7H,8H-pyrano[4,3-b]pyridine-3-carbonitrile; 2-Chloro-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile; 1250840-53-9; 2-Chloro-5H,7H,8H-pyrano[4,3-b]pyridine-3-carbonitrile; Pyrano[4,3-b]pyridine-3-carbonitrile, 2-chloro-7,8-dihydro-5H-; AKOS026714023; Z57127455
EINECS	Contact for details

Quality Control

Our 2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-B]Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.