Description

1-(2,2,2-Trifluoroethyl)-2-Methylpiperazine is a specialized fluorinated piperazine derivative, a key building block in modern synthetic chemistry. Its value lies in the unique trifluoroethyl group, which can significantly alter the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where enhanced lipophilicity, bioavailability, or metabolic stability is desired.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and catalysts used in asymmetric synthesis and other advanced chemical transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require fluorinated components for specific performance characteristics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)-2-Methylpiperazine
CAS No.	1250814-08-4
Molecular Formula	C7H13F3N2
Molecular Weight	182.19 g/mol
Synonyms	2-Methyl-1-(2,2,2-trifluoroethyl)piperazine; 2-Methyl-1-(trifluoroethyl)piperazine; 1-(Trifluoroethyl)-2-methylpiperazine; N-(2,2,2-Trifluoroethyl)-2-methylpiperazine; 2-Methyl-N-(2,2,2-trifluoroethyl)piperazine; 2-Methyl-1-(2,2,2-trifluoroethyl)-piperazine; 1-(2,2,2-Trifluoroethyl)-2-methyl-piperazine
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)-2-Methylpiperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.