Description

1-(5-Chloropyridin-2-Yl)-3-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate featuring a chloropyridine and methylpiperazine scaffold. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting neurological disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its heterocyclic structure.
• Ligand Synthesis: Serves as a precursor for creating complex ligands in catalytic and material science research.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	1-(5-Chloropyridin-2-Yl)-3-Methylpiperazine
CAS No.	1250773-22-8
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	3-Methyl-1-(5-chloro-2-pyridinyl)piperazine; 1-(5-Chloro-2-pyridinyl)-3-methylpiperazine; 3-Methyl-1-(5-chloropyridin-2-yl)piperazine; 1-(5-Chloro-pyridin-2-yl)-3-methyl-piperazine; 1250773-22-8; 5-Chloro-2-(3-methylpiperazin-1-yl)pyridine; 1-(5-Chloropyridin-2-yl)-3-methylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(5-Chloropyridin-2-Yl)-3-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure containers are sealed properly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.