Description

1-[(2-Methyl-1,3-Thiazol-5-Yl)Methyl]Piperazine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole-piperazine scaffold imparts specific biological activity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in drug discovery and process development. CAS No. 1250118-20-7.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Research: Used in the development of new generation pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Reagent: Serves as a versatile precursor for constructing more complex molecular architectures in academic and industrial organic chemistry laboratories.
• Ligand and Catalyst Development: Potential utility in the design of novel ligands for metal catalysis or as a scaffold in material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	1-[(2-Methyl-1,3-Thiazol-5-Yl)Methyl]Piperazine
CAS No.	1250118-20-7
Molecular Formula	C9H15N3S
Molecular Weight	197.30 g/mol
Synonyms	5-(Piperazin-1-ylmethyl)-2-methyl-1,3-thiazole; 2-Methyl-5-(piperazin-1-ylmethyl)thiazole; 1-[(2-Methyl-1,3-thiazol-5-yl)methyl]piperazine; 2-Methyl-5-(piperazin-1-ylmethyl)-1,3-thiazole; (2-Methyl-1,3-thiazol-5-ylmethyl)piperazine; Piperazine, 1-[(2-methyl-5-thiazolyl)methyl]-; 1250118-20-7
EINECS	Contact for details

Quality Control

Our 1-[(2-Methyl-1,3-Thiazol-5-Yl)Methyl]Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with cGMP standards for advanced pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.