Description

3-Cyclopropyl-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid is a high-value heterocyclic carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its fused triazolopyridine scaffold, which is a privileged structure for modulating biological activity and physicochemical properties in drug discovery. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile triazolopyridine core.
• Agrochemical Development: Potential intermediate in creating new fungicides or herbicides with novel modes of action.
• Ligand Synthesis: The carboxylic acid functionality allows for conjugation, making it useful for creating chelating agents or catalysts.
• Material Science Precursor: Can be utilized in the development of organic electronic materials or metal-organic frameworks (MOFs).
• Bioconjugation: Serves as a starting point for creating labeled compounds or probes for biochemical assays.

Basic Information

Product Name	3-Cyclopropyl-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid
CAS No.	1248926-27-3
Molecular Formula	C10H9N3O2
Molecular Weight	203.20 g/mol
Synonyms	3-Cyclopropyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid; 6-Carboxy-3-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridine; 3-Cyclopropyl-1,2,4-triazolo[4,3-a]pyridine-6-carboxylic acid; 1248926-27-3; CHEMBL3185990; ZINC000006456006; AKOS025147444; BDBM50389357
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-[1,2,4]Triazolo[4,3-A]Pyridine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.