Description

Methyl 1-(3-Chloropropyl)Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1248045-82-0. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering precise structural control for medicinal chemists. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• CNS Drug Development: Serves as a core scaffold for compounds targeting neurological and psychiatric disorders.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the piperidine-4-carboxylate moiety with a functionalized side chain.
• Custom Synthesis Projects: Supplied for contract research and manufacturing (CRAM) organizations for bespoke chemical production.
• Academic Research: Used in university and institutional labs for methodological development and pharmacological studies.

Basic Information

Product Name	Methyl 1-(3-Chloropropyl)Piperidine-4-Carboxylate
CAS No.	1248045-82-0
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	Methyl 1-(3-chloropropyl)-4-piperidinecarboxylate; 4-Piperidinecarboxylic acid, 1-(3-chloropropyl)-, methyl ester; Methyl 1-(3-chloropropyl)piperidine-4-carboxylate; 1-(3-Chloropropyl)piperidine-4-carboxylic acid methyl ester; Methyl 1-(γ-chloropropyl)isonipecotate; Methyl 1-(3-chloropropyl)isonipecotate; Isonipecotic acid, 1-(3-chloropropyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1-(3-Chloropropyl)Piperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.