Description

1-(5-Bromopyridin-3-Ylsulfonyl)Piperazine CAS NO 1247854-69-8 is a high-purity, functionalized piperazine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmacophore and versatile building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Inhibitor Development: Employed in the creation of enzyme inhibitors and receptor ligands due to its sulfonyl and bromopyridyl functional groups.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Piperazine
CAS No.	1247854-69-8
Molecular Formula	C9H12BrN3O2S
Molecular Weight	306.18 g/mol
Synonyms	1-[(5-Bromo-3-pyridinyl)sulfonyl]piperazine; 5-Bromo-3-(piperazine-1-sulfonyl)pyridine; 1-(5-Bromopyridine-3-sulfonyl)piperazine; Piperazine, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1247854-69-8; 5-Bromo-3-piperazin-1-ylsulfonylpyridine; 3-(Piperazine-1-sulfonyl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.