Description

1-[(2-Methylpropan-2-Yl)Oxycarbonyl]-5-Oxopiperazine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the piperazine carboxylic acid derivative class. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly protease inhibitors.
• Peptide Mimetic Research: Used in the design and development of peptidomimetics for therapeutic applications.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Employed in the scale-up and optimization of API manufacturing routes under cGMP conditions.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) due to its reactive carboxylic acid group.
• Chemical Biology: Utilized as a tool compound for probing enzyme active sites and biological pathways.

Basic Information

Product Name	1-[(2-Methylpropan-2-Yl)Oxycarbonyl]-5-Oxopiperazine-2-Carboxylic Acid
CAS No.	1246553-28-5
Molecular Formula	C10H16N2O5
Molecular Weight	244.25 g/mol
Synonyms	5-Oxo-1-[(2-methyl-2-propanyl)oxycarbonyl]-2-piperazinecarboxylic acid; 1-Boc-5-oxopiperazine-2-carboxylic acid; 1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid; Boc-5-oxopiperazine-2-COOH; tert-Butyl 5-oxo-2-(carboxymethyl)piperazine-1-carboxylate (tautomer); 1-N-Boc-5-oxopiperazine-2-carboxylic acid; 2-Piperazinecarboxylic acid, 5-oxo-1-[(2-methyl-2-propanyl)oxycarbonyl]-
EINECS	Contact for details

Quality Control

Our 1-[(2-Methylpropan-2-Yl)Oxycarbonyl]-5-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.