Description

3-(2-Fluoro-Phenyl)-Piperazin-2-One is a high-purity fluorinated piperazinone derivative, a crucial building block in modern pharmaceutical and agrochemical research and development. This compound is valued for its role as a key synthetic intermediate, enabling the creation of novel molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and psychiatric disorder treatments.
• Agrochemical Research: Serves as a building block for developing new crop protection agents, herbicides, and fungicides.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and high-throughput screening libraries to discover new drug candidates.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-(2-Fluoro-Phenyl)-Piperazin-2-One
CAS No.	1246553-07-0
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	2-Fluoro-N-(2-oxopiperazin-1-yl)benzamide; 1-(2-Fluorobenzoyl)piperazin-2-one; 3-(2-Fluorophenyl)piperazin-2-one; 2-Fluoro-N-(2-oxopiperazin-1-yl)benzenecarboxamide; 1-(2-Fluorobenzoyl)-1,4-diazepan-2-one; 1246553-07-0; AKOS026714095; ZINC000103048666
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoro-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.