Description

Ethyl 6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into kinase inhibitors and other targeted therapies. It is essential for pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Integral to the process development and scale-up of new active pharmaceutical ingredients for oncology and inflammatory diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process optimization services.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	Ethyl 6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	1246552-63-5
Molecular Formula	C10H9N3O3
Molecular Weight	219.20 g/mol
Synonyms	Ethyl 6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-6-one, 4-ethyl ester; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6,7-dihydro-6-oxo-, ethyl ester; 6-Oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid ethyl ester; CAS 1246552-63-5; Pyrazolopyridine derivative 1246552-63-5.
EINECS	Contact for details

Quality Control

Our Ethyl 6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.