Description

tert-Butyl 3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate CAS NO 1246551-25-6 is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic imidazopyrazine scaffold. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new drugs, especially those targeting central nervous system (CNS) disorders and other specialized treatments.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• CNS Drug Development: Particularly valuable for constructing molecules targeting neurological pathways due to its imidazopyrazine core.
• Contract Synthesis: Supplied to CDMOs for custom synthesis projects under cGMP or research-grade conditions.
• Process Chemistry: Employed in route scouting and scale-up activities for new chemical entities (NCEs).
• Academic Research: Utilized in universities and research institutes for exploring new heterocyclic chemistry and bioactivity.

Basic Information

Product Name	tert-Butyl 3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate
CAS No.	1246551-25-6
Molecular Formula	C11H17N3O3
Molecular Weight	239.27 g/mol
Synonyms	7-(tert-Butoxycarbonyl)-3-oxohexahydroimidazo[1,5-a]pyrazine; tert-Butyl 3-oxo-1,2,3,5,6,7-hexahydroimidazo[1,5-a]pyrazine-7-carboxylate; 1,2,3,5,6,7-Hexahydroimidazo[1,5-a]pyrazine-3-one, 7-[(1,1-dimethylethoxy)carbonyl]-; BOC-3-oxo-hexahydroimidazo[1,5-a]pyrazine-7-carboxylate; 3-Oxo-hexahydroimidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester; 1246551-25-6; tert-Butyl 3-oxohexahydro-1H-imidazo[1,5-a]pyrazine-7(5H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing specific results for identity, assay, purity, and related substances are available upon request. We support development with both research and cGMP-grade material as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.