Description

3-(3-Bromo-Phenyl)-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its piperazinone core and brominated aromatic ring. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of more complex heterocyclic compounds due to its reactive functional groups.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	3-(3-Bromo-Phenyl)-Piperazin-2-One
CAS No.	1246550-36-6
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	3-(3-Bromophenyl)piperazin-2-one; 1-(3-Bromophenyl)-2-oxopiperazine; 3-(3-Bromophenyl)-2-piperazinone; 2-Piperazinone, 3-(3-bromophenyl)-; 3-(3-Bromo-phenyl)-piperazin-2-one; 1246550-36-6
EINECS	Contact for details

Quality Control

Our production of 3-(3-Bromo-Phenyl)-Piperazin-2-One adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support customer audits to verify our GMP-compliant manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.