Description

1-Methylpiperazine-2-Carboxylic Acid Dihydrochloride is a high-purity, pharmaceutically relevant building block, primarily valued for its role as a key intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its significance lies in providing a functionalized piperazine scaffold, which is a privileged structure in medicinal chemistry for developing compounds with targeted biological activity. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on oncology, central nervous system (CNS), and anti-infective drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing a piperazine moiety.
• API Synthesis: Used in the multi-step production of Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry R&D: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization during drug discovery.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide analogs and mimetics due to its carboxylic acid functionality.
• Ligand and Catalyst Development: Can be utilized to create novel ligands for metal complexes or organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	1-Methylpiperazine-2-Carboxylic Acid Dihydrochloride
CAS No.	1246550-14-0
Molecular Formula	C7H16Cl2N2O2
Molecular Weight	231.12 g/mol
Synonyms	2-Piperazinecarboxylic acid, 1-methyl-, dihydrochloride; 1-Methyl-2-piperazinecarboxylic acid dihydrochloride; (1-Methylpiperazin-2-yl)carboxylic acid dihydrochloride; 1-Methylpiperazine-2-carboxylic acid hydrochloride (1:2); 1-Methyl-2-carboxypiperazine dihydrochloride; 1-Methylhomopiperazine-2-carboxylic acid dihydrochloride; 1246550-14-0
EINECS	Contact for details

Quality Control

Our 1-Methylpiperazine-2-Carboxylic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.