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n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-Phytosphingosine CAS NO 1246355-60-1


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CAS No.:1246355-60-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-Phytosphingosine is a sophisticated synthetic lipid probe, expertly engineered by conjugating a BODIPY fluorophore to a phytosphingosine backbone via a long-chain fatty acyl linker. This compound matters for researchers and developers requiring precise, fluorescent labeling of sphingolipids to study their metabolism, trafficking, and localization in complex biological systems. It is primarily needed by the life sciences sector, including academic research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on lipidomics, cell biology, and high-content screening applications.

Application

  • Fluorescent Labeling of Sphingolipids: Used as a vital tool for tagging and visualizing phytosphingosine and its metabolites in live-cell imaging and fluorescence microscopy studies.
  • Lipid Trafficking & Metabolism Research: Enables real-time tracking of sphingolipid transport, sorting, and metabolic pathways within cellular membranes.
  • High-Content Screening (HCS): Serves as a key reagent in automated screening assays to identify modulators of sphingolipid-related enzymes or pathways in drug discovery.
  • Biomembrane & Lipid Raft Studies: Acts as a fluorescent probe to investigate the dynamics, organization, and function of lipid rafts and membrane microdomains.
  • Diagnostic Assay Development: Utilized in the development of sensitive fluorescence-based diagnostic tests for metabolic disorders involving sphingolipid imbalances.
  • Bioconjugation & Probe Synthesis: Provides a versatile building block for creating more complex fluorescent conjugates or sensor molecules targeting specific lipid-protein interactions.

Basic Information

Product Name n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-Phytosphingosine
CAS No. 1246355-60-1
Molecular Formula C40H67BF2N2O5
Molecular Weight 704.79 g/mol
Synonyms BODIPY FL C11-Phytosphingosine; BODIPY® FL C11-Phytosphingosine; N-[(11-{3,5-Dimethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacen-8-yl}undecanoyl]phytosphingosine; Fluorescent Phytosphingosine Probe; BODIPY-FL labeled Phytosphingosine; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoic Acid Phytosphingosine Amide; Lipidomics Fluorescent Tracer
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Quality Control

Our high-purity biochemical reagents undergo rigorous quality testing to ensure batch-to-batch consistency and performance reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with internal quality standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Under these conditions, the product is stable for at least 24 months from the date of receipt.

Specification

Item Specification
Appearance Orange to red solid or film
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 95%
Excitation/Emission Maxima ~503 nm / ~512 nm
Solubility Soluble in DMSO, DMF, ethanol; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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