Description

n-Lauroyl-D-Erythro-Sphingosyl Phosphoethanolamine (C17 Base) is a high-purity, synthetic sphingolipid derivative, specifically a C17 base ceramide phosphoethanolamine. This compound is a critical research-grade biochemical and a valuable building block for advanced lipidomic studies and the development of novel lipid-based formulations. It is primarily utilized by pharmaceutical researchers, cosmetic scientists, and biotechnology companies engaged in studying cell membrane biology, signal transduction pathways, and developing next-generation dermal delivery systems.

Application

• Biochemical & Lipidomic Research: As a standard or reagent for studying sphingolipid metabolism, cell signaling, and apoptosis mechanisms.
• Pharmaceutical Development: Investigation as a potential active pharmaceutical ingredient (API) or excipient in targeted drug delivery systems, particularly for skin-related therapies.
• Advanced Cosmetic Science: Formulation of high-end skincare products aimed at enhancing skin barrier function, moisture retention, and anti-aging properties.
• Cell Culture & Media Supplement: Used in specialized cell culture applications to study the effects of specific sphingolipids on cell growth and differentiation.
• Analytical Standard: Serves as a certified reference material (CRM) for the qualitative and quantitative analysis of complex lipid mixtures via HPLC, LC-MS, or other chromatographic techniques.
• Liposome & Nanoparticle Synthesis: A key phospholipid component for constructing stable, functionalized liposomes and lipid nanoparticles (LNPs) for encapsulation and delivery.

Basic Information

Item	Detail
Product Name	n-Lauroyl-D-Erythro-Sphingosyl Phosphoethanolamine (C17 Base)
CAS No.	1246303-21-8
Molecular Formula	C31H62N2O7P
Molecular Weight	605.81 g/mol
Synonyms	Lauroyl Sphingosyl Phosphoethanolamine; N-Lauroyl-D-erythro-sphingosylphosphorylethanolamine; D-erythro-Sphingosine, N-(1-oxododecyl)-, 1-phosphoethanolamine; Ceramide (d18:1/12:0) Phosphoethanolamine; C17 Sphingosine Base Ceramide PE; C17 Ceramide Phosphoethanolamine; N-Lauroyl-sphingosine-1-phosphoethanolamine; Sphingolipid C17 Base
EINECS	Contact for details

Quality Control

Our n-Lauroyl-D-Erythro-Sphingosyl Phosphoethanolamine (C17 Base) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for structural confirmation, and NMR for identity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed vial at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.