Description

n-Lignoceroyl-Ceramide-1-Phosphate (Ammonium Salt) is a high-purity, synthetic sphingolipid derivative, specifically a ceramide-1-phosphate (C1P) analog with a very long-chain lignoceroyl (C24:0) fatty acid moiety. This compound is a critical research-grade biochemical tool for investigating the role of C1P in cellular signaling pathways, particularly those involving inflammation, cell proliferation, and apoptosis. It is essential for scientists and product developers in the pharmaceutical, biotechnology, and advanced cosmetics industries who require well-defined, high-quality lipid standards and intermediates for drug discovery, formulation, and mechanism-of-action studies.

Application

• Biochemical Research & Drug Discovery: Used as a standard, substrate, or inhibitor in enzymatic assays and signaling pathway studies to elucidate the biological functions of Ceramide-1-Phosphate.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate or active pharmaceutical ingredient (API) precursor in the development of novel therapeutics targeting inflammatory diseases, cancer, and metabolic disorders.
• Lipidomics & Analytical Standards: An essential reference standard for mass spectrometry-based lipidomic profiling, enabling accurate identification and quantification of C1P species in biological samples.
• Advanced Cosmetic Actives: Investigated for use in high-end skincare formulations for its potential role in modulating skin barrier function, hydration, and anti-inflammatory responses.
• Cell Culture & Media Supplements: Employed in specialized cell culture systems to study lipid-mediated cell signaling and membrane dynamics.
• Enzyme Kinetics & Characterization: A substrate for enzymes like ceramide kinase (CERK), facilitating the study of enzyme activity, inhibition, and kinetics.

Basic Information

Product Name	n-Lignoceroyl-Ceramide-1-Phosphate (Ammonium Salt)
CAS No.	1246303-20-7
Molecular Formula	C46H95N2O7P
Molecular Weight	819.24 g/mol
Synonyms	Ceramide-1-Phosphate (C24:0, Ammonium Salt); N-Lignoceroyl-D-erythro-sphingosine-1-phosphate ammonium salt; C1P (24:0); N-Tetracosanoyl-sphingosine-1-phosphate ammonium salt; Lignoceroyl Ceramide Phosphate; D-erythro-Ceramide (d18:1/24:0) 1-phosphate ammonium salt; CER[NDS](d18:1/24:0) 1-phosphate ammonium salt; Ammonium N-(1,3-dihydroxyoctadec-4-en-2-yl)tetracosanamide hydrogen phosphate
EINECS	Contact for details

Quality Control

Our n-Lignoceroyl-Ceramide-1-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS and NMR for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research and development standards. Specifications can be tailored to meet the requirements of cGMP, ICH guidelines, or other specific pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere (e.g., argon or nitrogen) and kept in a desiccated environment. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Assay (by P NMR)	≥ 98%
Water Content (KF)	≤ 2.0%
Solvent Residues (GC)	Meets ICH limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.