Description

n-Palmitoyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt) is a high-purity, synthetic phospholipid derivative of dihydroceramide, a key intermediate in the sphingolipid biosynthesis pathway. This compound is critical for advanced research into cellular signaling, apoptosis, and lipid metabolism, offering a defined and stable alternative to natural ceramides. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and formulation scientists in the development of novel therapeutics, advanced drug delivery systems, and high-end cosmetic actives.

Application

• Biochemical Research: As a critical tool for studying sphingolipid biology, ceramide signaling pathways, and cellular stress responses.
• Pharmaceutical Development: Investigation as a potential active pharmaceutical ingredient (API) or intermediate for therapies targeting cancer, inflammatory diseases, and metabolic disorders.
• Lipidomics & Analytical Standards: Use as a certified reference standard for mass spectrometry and chromatographic analysis in lipid profiling.
• Advanced Cosmetic Formulations: Incorporation into high-performance skincare products for its potential role in modulating skin barrier function and cellular communication.
• Drug Delivery Systems: Exploration as a component in liposomal and nanoparticle formulations for targeted drug delivery.
• Cell Culture & Media Supplements: Used in specialized cell culture applications to study lipid-mediated effects on cell growth and differentiation.

Basic Information

Product Name	n-Palmitoyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt)
CAS No.	1246303-17-2
Molecular Formula	C₃₄H₇₁N₂O₆P
Molecular Weight	634.92 g/mol
Synonyms	Dihydroceramide-1-phosphate (C16:0, D-erythro, Ammonium Salt); N-Palmitoyldihydroceramide 1-phosphate ammonium salt; (2S,3R)-2-Hexadecanamido-3-hydroxyoctadecyl dihydrogen phosphate ammonium salt; D-erythro-C16-Dihydroceramide-1-phosphate ammonium salt; Cer(d18:0/16:0)-1P ammonium salt; Dihydroceramide phosphate (C16); Ammonium (2S,3R)-2-(palmitoylamino)-3-hydroxyoctadecyl phosphate
EINECS	Contact for details

Quality Control

Our n-Palmitoyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting research reproducibility and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.