Description

1,2-Dipalmitoyl- Sn -Glycero-3-[Phospho- Rac -(3-Lysyl(1-Glycerol))] (Chloride Salt) is a high-purity, synthetic phospholipid derivative, specifically a lysylphosphatidylglycerol (LPG) analog, essential for advanced formulation research and development. This compound is critical for creating model membrane systems to study lipid-protein interactions, antimicrobial mechanisms, and drug delivery vehicle stability. It is primarily utilized by research scientists and product developers in the pharmaceutical, biotechnology, and advanced material science sectors for developing next-generation liposomal formulations and biomimetic coatings.

Application

• Liposomal Drug Delivery Systems: As a key component for formulating stable, targeted liposomes, particularly for antibiotics and anticancer therapies.
• Biomimetic Membrane Research: For constructing model bacterial membranes to study the mechanism of action of cationic antimicrobial peptides (AMPs) and host-defense peptides.
• Surface Chemistry & Coatings: Used to create functionalized surfaces and lipid bilayers on sensors or medical devices to modulate biocompatibility and cellular response.
• Biophysical Studies: Essential for investigating lipid bilayer properties, phase behavior, and electrostatic interactions using techniques like NMR, calorimetry, and fluorescence spectroscopy.
• Vaccine Adjuvant Development: As a potential immunostimulatory component in lipid-based adjuvant systems to enhance vaccine efficacy.
• Diagnostic Reagent Formulation: In the development of lipid-based reagents for clinical diagnostics and imaging.

Basic Information

Product Name	1,2-Dipalmitoyl- Sn -Glycero-3-[Phospho- Rac -(3-Lysyl(1-Glycerol))] (Chloride Salt)
CAS No.	1246303-06-9
Molecular Formula	C44H88N2O12PCl
Molecular Weight	887.62 g/mol
Synonyms	DPPG-Lys; 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(3-lysyl(1-glycerol)), chloride salt; Lysyl-PG (16:0/16:0); Lysylphosphatidylglycerol, dipalmitoyl; L-α-Phosphatidylglycerol (dipalmitoyl) lysyl derivative; (3R)-3-({[(2R)-2,3-Bis(hexadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropyl (2S)-2,6-diaminohexanoate chloride; PG-Lys(C16:0); DPPG-Lysinamide
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl- Sn -Glycero-3-[Phospho- Rac -(3-Lysyl(1-Glycerol))] (Chloride Salt) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 3.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.