Description

n-Nervonoyl-1-Desoxymethylsphinganine (M17:0/24:1) is a high-purity, synthetic sphingolipid analog, a critical building block for advanced lipidomics research and the development of novel bioactive compounds. This compound is essential for scientists investigating cell membrane structure, signaling pathways, and lipid metabolism due to its defined structure and purity. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for use as a reference standard, a synthetic intermediate, and in metabolic studies.

Application

• Lipidomics Research: Serves as a critical internal or external standard for the precise quantification and identification of complex sphingolipids in biological samples using mass spectrometry (MS) and liquid chromatography (LC-MS).
• Biochemical Tool Compound: Used to study the role of specific sphingolipid species in cell signaling, apoptosis, and membrane dynamics in vitro and in vivo.
• Pharmaceutical Intermediate: Acts as a key synthetic precursor in the research and development of novel therapeutic agents targeting sphingolipid-related diseases, such as cancer, metabolic disorders, and neurodegenerative conditions.
• Reference Material: Provides a certified, high-purity standard for analytical method development, validation, and quality control in laboratory and industrial settings.
• Metabolic Pathway Analysis: Enables tracing and understanding of sphingolipid biosynthesis and catabolism pathways through stable isotope-labeled derivative synthesis.

Basic Information

Product Name	n-Nervonoyl-1-Desoxymethylsphinganine (M17:0/24:1)
CAS No.	1246298-61-2
Molecular Formula	C41H79NO2
Molecular Weight	618.08 g/mol
Synonyms	N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]tetracos-15-enamide; M17:0/24:1 Sphinganine; D-erythro-Sphinganine, N-nervonoyl-; N-Nervonoylsphinganine; (2S,3R)-2-(Nervonoylamino)octadecane-1,3-diol; 1-Desoxymethylsphinganine M17:0/24:1; Sphingolipid analog M17:0/24:1
EINECS	Contact for details

Quality Control

Our n-Nervonoyl-1-Desoxymethylsphinganine (M17:0/24:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) providing results for assay, identity confirmation (NMR, MS), and purity profile (HPLC) is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. For long-term storage, desiccate. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 97% (by NMR)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.