Description

(S)-n-(Pyrrolidin-3-Yl)Acetamide Hydrochloride is a high-purity chiral intermediate and building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which are critical for constructing molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation and Probe Synthesis: The amine functionality allows for its use in creating biochemical probes and conjugated molecules for diagnostic applications.
• Academic & Industrial R&D: Employed in fundamental organic chemistry research to explore new synthetic methodologies and novel heterocyclic compounds.

Basic Information

Product Name	(S)-n-(Pyrrolidin-3-Yl)Acetamide Hydrochloride
CAS No.	1246277-44-0
Molecular Formula	C6H13ClN2O
Molecular Weight	164.63 g/mol
Synonyms	(S)-1-(2-Aminoethyl)pyrrolidin-2-one Hydrochloride; (S)-2-(2-Oxopyrrolidin-1-yl)ethanamine Hydrochloride; (S)-N-(Pyrrolidin-3-yl)acetamide HCl; (3S)-1-Acetylpyrrolidin-3-amine Hydrochloride; (S)-3-Acetamidopyrrolidine Hydrochloride; (S)-N-(3-Pyrrolidinyl)acetamide Hydrochloride; 1246277-44-0; (S)-Pyrrolidin-3-yl-acetamide hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-n-(Pyrrolidin-3-Yl)Acetamide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards, and custom purity grades, including GMP standards for advanced applications, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.