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Hooc-Peg7-Ch2Ch2Cooh CAS NO 1246189-43-4


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CAS No.:1246189-43-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Hooc-Peg7-Ch2Ch2Cooh is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a carboxylic acid group at each terminus. This compound is engineered to serve as a versatile linker and spacer molecule in advanced bioconjugation and materials science applications. It is essential for researchers and manufacturers in the pharmaceutical, diagnostics, and nanotechnology sectors who require reliable, water-soluble crosslinkers with defined chain lengths for creating stable conjugates.

Application

  • Bioconjugation and Protein Modification: Used to link peptides, proteins, or antibodies to surfaces, nanoparticles, or other biomolecules, improving solubility and stability.
  • Drug Delivery System Development: Acts as a functionalized PEG spacer in the synthesis of prodrugs and polymer-drug conjugates to enhance pharmacokinetics.
  • Diagnostic Reagent Synthesis: Employed in the preparation of labeled probes and assay components for immunoassays and biosensors.
  • Hydrogel and Biomaterial Fabrication: Serves as a crosslinking agent or functional monomer in creating PEG-based hydrogels for tissue engineering and controlled release.
  • Surface Functionalization: Used to introduce carboxylic acid groups onto nanoparticles, quantum dots, or other substrates for subsequent covalent attachment.
  • Polymer Chemistry: Functions as a macromonomer or chain extender in the synthesis of functionalized copolymers and block copolymers.

Basic Information

Product Name Hooc-Peg7-Ch2Ch2Cooh
CAS No. 1246189-43-4
Molecular Formula C20H36O12
Molecular Weight 468.5 g/mol
Synonyms 8,11,14,17,20,23,26-Heptaoxaoctacosanedioic acid; α,ω-Dicarboxy PEG7; 3,6,9,12,15,18,21-Heptaoxatricosanedioic acid; PEG-7 dicarboxylic acid; HOOC-PEG7-COOH; Dicarboxy-terminated heptaethylene glycol; 1,1'-[1,2-Ethanediylbis(oxy-3,1-propanediyl)]bis[1,4,7,10,13-pentaoxahexadecan-16-oic acid]; 2,2'-(Ethane-1,2-diylbis(oxy))bis(acetic acid) PEG derivative
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Quality Control

Our Hooc-Peg7-Ch2Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR and FT-IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and commercial applications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white waxy solid or viscous liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Acid Value (Titration) Theoretical ± 5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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