Description

4-(2-Hydroxyethyl)-1-Piperazinyl](2-Piperidinyl)-Methanone Hydrochloride is a high-purity, functionalized piperazine-piperidine hybrid compound offered as a hydrochloride salt. This advanced pharmaceutical intermediate is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those with neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile piperazine-piperidine scaffold.
• API Development: Serves as a precursor in the development and scale-up of new active pharmaceutical ingredients.
• Chemical Synthesis: Employed in organic synthesis to introduce specific amine and amide functionalities into complex molecules.
• Bioconjugation & Probe Development: Potential use in creating biochemical probes and conjugates for diagnostic or research purposes.

Basic Information

Product Name	4-(2-Hydroxyethyl)-1-Piperazinyl](2-Piperidinyl)-Methanone Hydrochloride
CAS No.	1246172-56-4
Molecular Formula	C12H23N3O2 • HCl
Molecular Weight	277.79 g/mol (Free base: 241.33 g/mol)
Synonyms	1-[2-(2-Hydroxyethyl)-1-piperazinyl]-2-piperidin-1-ylethanone hydrochloride; 2-(4-(2-Piperidine-1-carbonyl)piperazin-1-yl)ethanol hydrochloride; 1-Piperazineethanol, 4-(2-piperidinylcarbonyl)-, hydrochloride; (2-Piperidinyl)[4-(2-hydroxyethyl)-1-piperazinyl]methanone hydrochloride; N-(2-Hydroxyethyl)-N'-(1-oxo-2-piperidinyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(2-Hydroxyethyl)-1-Piperazinyl](2-Piperidinyl)-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.