Description

5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique halogenated pyrrolopyridine core makes it a critical intermediate for constructing complex molecular architectures with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study biological pathways and protein functions.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and organoiodine chemistry.

Basic Information

Product Name	5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carboxylic Acid
CAS No.	1246088-58-3
Molecular Formula	C8H4ClIN2O2
Molecular Weight	322.49 g/mol
Synonyms	4-Carboxy-5-chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 5-chloro-6-iodo-; 5-Chloro-6-iodo-4-carboxy-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine-4-carboxylate (anion form)
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.