Description

2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-8-ol is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its unique fused dioxino-pyridine structure, which is integral to the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-performance compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for designing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes for biological imaging and assay development.
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in academic and contract research organizations (CROs).

Basic Information

Product Name	2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-8-ol
CAS No.	1246088-43-6
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	8-Hydroxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridin-8-ol, 2,3-dihydro-; 2,3-Dihydro-1,4-dioxino[2,3-b]pyridin-8-ol; 8-Hydroxydioxinopyridine; DHPO Intermediate; CAS 1246088-43-6
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-8-ol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.