Description

(6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine is a high-value pyridine derivative building block characterized by its chloro and trifluoromethyl substituents. This compound is essential for medicinal chemistry and agrochemical research, where its unique halogenated structure enables the synthesis of novel active ingredients with enhanced properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and crop protection industries for creating advanced intermediates and final active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine
CAS No.	1245915-89-2
Molecular Formula	C7H6ClF3N2
Molecular Weight	210.58 g/mol
Synonyms	1-(6-Chloro-5-(trifluoromethyl)pyridin-3-yl)methanamine; 3-Pyridinemethanamine, 6-chloro-5-(trifluoromethyl)-; (6-Chloro-5-trifluoromethyl-pyridin-3-yl)-methylamine; 5-(Aminomethyl)-2-chloro-3-(trifluoromethyl)pyridine; 2-Chloro-3-(trifluoromethyl)-5-(aminomethyl)pyridine; 6-Chloro-5-(trifluoromethyl)nicotinylamine; 3-(Aminomethyl)-6-chloro-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our (6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.