Description

1-(6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of agrochemicals and small-molecule therapeutics. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Chemical Research & Development: Serves as a versatile synthon for organic synthesis, enabling the introduction of both chloro and trifluoromethyl functional groups.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional materials.

Basic Information

Product Name	1-(6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone
CAS No.	1245915-41-6
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	6-Chloro-5-(trifluoromethyl)pyridin-3-yl methyl ketone; 1-[6-Chloro-5-(trifluoromethyl)-3-pyridinyl]ethanone; 3-Acetyl-6-chloro-5-(trifluoromethyl)pyridine; Ethanone, 1-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]-; 1245915-41-6
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.