Description

Methyl 3-Hydroxy-6-(Trifluoromethyl)Pyridine-2-Carboxylate is a high-value pyridine derivative and a key synthetic intermediate prized for its unique trifluoromethyl and ester functionalities. This compound is essential for researchers and manufacturers requiring precise molecular building blocks for advanced chemical synthesis. It is primarily targeted at the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-Hydroxy-6-(Trifluoromethyl)Pyridine-2-Carboxylate
CAS No.	1245915-35-8
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	Methyl 3-hydroxy-6-(trifluoromethyl)picolinate; 2-Pyridinecarboxylic acid, 3-hydroxy-6-(trifluoromethyl)-, methyl ester; 6-(Trifluoromethyl)-3-hydroxypyridine-2-carboxylic acid methyl ester; 3-Hydroxy-6-trifluoromethyl-pyridine-2-carboxylic acid methyl ester; Methyl 3-hydroxy-6-(trifluoromethyl)-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Hydroxy-6-(Trifluoromethyl)Pyridine-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.