Description

1-Piperazinecarboxylic Acid, 4-(5-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-value, protected piperazine-pyridine hybrid intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex molecules, particularly in the creation of kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Chemical Synthesis: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological research due to its reactive amino and ester functional groups.
• Academic Research: Employed in university and institutional labs for exploring new synthetic methodologies and novel heterocyclic chemistry.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(5-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1245914-05-9
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	tert-Butyl 4-(5-amino-3-pyridinyl)piperazine-1-carboxylate; 4-(5-Amino-3-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-4-(5-amino-3-pyridinyl)piperazine; 5-Amino-3-pyridinylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(5-aminopyridin-3-yl)piperazine-1-carboxylate; 4-(5-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(5-amino-3-pyridyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-(5-Amino-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.