Description

6-Chloro-2-(trifluoromethyl)nicotinonitrile is a high-value, multi-functional heterocyclic building block featuring a chloropyridine core substituted with both a nitrile and a trifluoromethyl group. This compound is essential for medicinal chemistry and agrochemical research, where its unique structure enables the synthesis of novel molecules with enhanced biological activity and metabolic stability. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for functionalized ligands and organic frameworks in the development of specialty polymers and electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	6-Chloro-2-(trifluoromethyl)nicotinonitrile
CAS No.	1245913-20-5
Molecular Formula	C7H2ClF3N2
Molecular Weight	206.55 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)nicotinonitrile; 6-Chloro-2-(trifluoromethyl)-3-cyanopyridine; 3-Cyano-6-chloro-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-6-chloronicotinonitrile; 1245913-20-5; 6-Chloro-2-trifluoromethylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(trifluoromethyl)nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.