Description

6,7-Dihydro-[1,2,3]triazolo[1,5-a]pyrazine-5(4H)-carboxylic acid tert-butyl ester is a high-purity, protected heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex nitrogen-containing scaffolds, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry: Used as a versatile scaffold for constructing fused triazolopyrazine libraries in structure-activity relationship (SAR) studies and high-throughput screening.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that utilize its unique heterocyclic core.
• Chemical Biology: Acts as a building block for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Material Science: Potential use in the synthesis of specialty polymers, ligands for catalysis, and organic electronic materials due to its rigid, nitrogen-rich structure.
• Process Chemistry: The tert-butyl ester protecting group facilitates selective synthetic transformations, making it valuable for multi-step industrial-scale synthesis.

Basic Information

Product Name	6,7-Dihydro-[1,2,3]triazolo[1,5-a]pyrazine-5(4H)-carboxylic acid tert-butyl ester
CAS No.	1245782-69-7
Molecular Formula	C11H16N4O2
Molecular Weight	236.27 g/mol
Synonyms	tert-Butyl 6,7-dihydro-4H-[1,2,3]triazolo[1,5-a]pyrazine-5-carboxylate; 4H-[1,2,3]Triazolo[1,5-a]pyrazine-5-carboxylic acid, 6,7-dihydro-, 1,1-dimethylethyl ester; 6,7-Dihydro-4H-[1,2,3]triazolo[1,5-a]pyrazine-5-carboxylic acid tert-butyl ester; BOC-protected triazolopyrazine; Triazolopyrazine tert-butyl ester; 1245782-69-7; tert-Butyl 5,6,7,8-tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine-5-carboxylate (tautomeric form)
EINECS	Contact for details

Quality Control

Our 6,7-Dihydro-[1,2,3]triazolo[1,5-a]pyrazine-5(4H)-carboxylic acid tert-butyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.