Description

tert-Butyl 7-Benzyl-2,7-Diazaspiro[4.5]Decane-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiro decane class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its complex spirocyclic scaffold which is instrumental in modulating the pharmacokinetic and pharmacodynamic properties of drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutics, particularly in the areas of central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of potent drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Used in the research and development of novel enzyme inhibitors due to its constrained, three-dimensional structure.
• Ligand Synthesis for Drug Discovery: Employed in the creation of sophisticated ligands for G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	tert-Butyl 7-Benzyl-2,7-Diazaspiro[4.5]Decane-2-Carboxylate
CAS No.	1245649-93-7
Molecular Formula	C20H30N2O2
Molecular Weight	330.47 g/mol
Synonyms	2,7-Diazaspiro[4.5]decane-2-carboxylic acid, 7-(phenylmethyl)-, 1,1-dimethylethyl ester; 7-Benzyl-2,7-diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; tert-Butyl 7-benzyl-2,7-diazaspiro[4.5]decane-2-carboxylate; 7-Benzyl-2-tert-butoxycarbonyl-2,7-diazaspiro[4.5]decane; 2-Boc-7-benzyl-2,7-diazaspiro[4.5]decane; Bn-DiaSpiro(Boc); CAS 1245649-93-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Benzyl-2,7-Diazaspiro[4.5]Decane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.