Description

6-Iodo-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine (CAS NO 1245647-65-7) is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a fused triazolopyridine scaffold with a reactive iodine substituent, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Employed in the creation of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential building block for advanced organic electronic materials and ligands in catalysis.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex substituents.

Basic Information

Item	Detail
Product Name	6-Iodo-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine
CAS No.	1245647-65-7
Molecular Formula	C6H4IN5
Molecular Weight	273.03 g/mol
Synonyms	6-Iodo-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 2-Amino-6-iodo-[1,2,4]triazolo[1,5-a]pyridine; 6-Iodo-2-amino-[1,2,4]triazolo[1,5-a]pyridine; 1245647-65-7; 6-Iodo-1,2,4-triazolo[1,5-a]pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Iodo-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment is to supply material that meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.