Description

Carbamic Acid, n-(6-Oxo-3-Piperidinyl)-, 1,1-Dimethylethyl Ester is a specialized organic building block featuring a piperidinone core protected by a tert-butyloxycarbonyl (Boc) group. This compound is of significant value in pharmaceutical research and development as a key intermediate for synthesizing complex molecules, particularly those targeting neurological and metabolic pathways. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries to construct novel active pharmaceutical ingredients (APIs) and investigate new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those containing a piperidine or piperidinone pharmacophore.
• Medicinal Chemistry Research: Used in the design and construction of compound libraries for high-throughput screening (HTS) against various biological targets.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Neurological & Metabolic Drug Synthesis: A key building block for developing potential therapeutics for central nervous system (CNS) disorders, pain management, and metabolic diseases.
• Peptidomimetic & Protease Inhibitor Synthesis: The Boc-protected amine functionality makes it valuable for creating peptide-like molecules and inhibitors of specific enzymes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	Carbamic Acid, n-(6-Oxo-3-Piperidinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1245646-80-3
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	tert-Butyl 3-amino-6-oxopiperidine-1-carboxylate; 1-Boc-3-amino-6-piperidinone; 3-Amino-6-oxopiperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-amino-6-piperidinone; 3-Amino-1-N-Boc-6-piperidinone; 3-Amino-6-piperidinone-1-carboxylic acid tert-butyl ester; N-Boc-3-amino-6-piperidinone; 3-Amino-6-oxo-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-(6-Oxo-3-Piperidinyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.