Description

tert-Butyl 4-(1-(Benzyloxycarbonyl)Azetidin-3-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new molecular entities.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for the production of target active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of specialized probes for studying biological pathways and target engagement.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Product Name	tert-Butyl 4-(1-(Benzyloxycarbonyl)Azetidin-3-Yl)Piperazine-1-Carboxylate
CAS No.	1245646-73-4
Molecular Formula	C20H29N3O4
Molecular Weight	375.47 g/mol
Synonyms	1,1-Dimethylethyl 4-[1-[(phenylmethoxy)carbonyl]-3-azetidinyl]-1-piperazinecarboxylate; 1-Boc-4-(1-Cbz-azetidin-3-yl)piperazine; tert-Butyl 4-[1-(benzyloxycarbonyl)azetidin-3-yl]piperazine-1-carboxylate; 4-(1-Cbz-azetidin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; 3-(4-Boc-piperazin-1-yl)azetidine-1-carboxylic acid benzyl ester; BOC-CBZ-Azetidine-Piperazine; Azetidin-3-yl-piperazine derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1-(Benzyloxycarbonyl)Azetidin-3-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.