Description

3-Hydroxy-1-(4-Methoxybenzyl)Piperidin-2-One is a high-purity, specialized organic compound with a defined piperidinone core structure. This molecule is of significant interest in advanced organic synthesis, serving as a versatile chiral building block or intermediate for the development of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for target molecules under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Employed as a building block requiring specific stereochemistry for the construction of enantiomerically pure compounds.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for methodological development and the study of novel synthetic transformations.

Basic Information

Product Name	3-Hydroxy-1-(4-Methoxybenzyl)Piperidin-2-One
CAS No.	1245644-82-9
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	1-[(4-Methoxyphenyl)methyl]-3-hydroxypiperidin-2-one; 3-Hydroxy-1-(4-methoxybenzyl)-2-piperidinone; 1-(4-Methoxybenzyl)-3-hydroxypiperidin-2-one; 3-Hydroxy-1-(p-methoxybenzyl)piperidin-2-one; 2-Piperidinone, 3-hydroxy-1-[(4-methoxyphenyl)methyl]-; 3-Hydroxy-1-(4-methoxybenzyl)piperidin-2-one; 1245644-82-9
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-1-(4-Methoxybenzyl)Piperidin-2-One is manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.