Description

(S)-1-Benzyl-3-Hydroxypiperidin-2-One is a high-purity chiral piperidinone derivative, a critical building block in modern pharmaceutical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D and fine chemical manufacturers need this material for creating novel therapeutic agents with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially in neurological and psychiatric drug discovery.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a specific (S)-configured piperidinone scaffold.
• Asymmetric Synthesis: Serves as a versatile precursor in asymmetric catalytic reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals and advanced materials.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical labs.

Basic Information

Product Name	(S)-1-Benzyl-3-Hydroxypiperidin-2-One
CAS No.	1245644-72-7
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	(S)-1-Benzyl-3-hydroxypiperidin-2-one; (3S)-1-Benzyl-3-hydroxypiperidin-2-one; (S)-1-Benzyl-3-hydroxy-2-piperidinone; 1-Benzyl-3-hydroxy-2-piperidinone, (S)-; 2-Piperidinone, 1-benzyl-3-hydroxy-, (3S)-; (S)-1-Benzyl-3-hydroxypiperidin-2-one CAS 1245644-72-7; (S)-1-Bn-3-hydroxypiperidin-2-one
EINECS	Contact for details

Quality Control

Our (S)-1-Benzyl-3-Hydroxypiperidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.