Description

8-Bromo-3-Iodoimidazo[1,2-A]Pyrazine CAS NO 1245644-46-5 is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which serves as a versatile scaffold for constructing complex pharmacophores and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, catalyst development, and the synthesis of novel electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small molecule drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Biology: Employed as a molecular probe or a tagged scaffold for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for palladium-catalyzed Suzuki, Stille, and Sonogashira cross-coupling reactions.
• Library Synthesis: A valuable input for combinatorial and parallel synthesis to generate diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	8-Bromo-3-Iodoimidazo[1,2-A]Pyrazine
CAS No.	1245644-46-5
Molecular Formula	C6H3BrIN3
Molecular Weight	323.92 g/mol
Synonyms	8-Bromo-3-iodoimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 8-bromo-3-iodo-; 1245644-46-5; 3-Iodo-8-bromoimidazo[1,2-a]pyrazine; 8-Bromo-3-iodo-imidazo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Iodoimidazo[1,2-A]Pyrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced material supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.