Description

2-(Benzyloxy)-5-Bromo-3-Nitropyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated and nitrated pyridine core. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated pyridine structure.
• Chemical Synthesis Building Block: The bromo and nitro functional groups make it a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization.
• Material Science Research: Investigated as a monomer or precursor for creating specialized polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO settings for method development and exploratory chemistry projects.

Basic Information

Product Name	2-(Benzyloxy)-5-Bromo-3-Nitropyridine
CAS No.	1245643-66-6
Molecular Formula	C12H9BrN2O3
Molecular Weight	309.12 g/mol
Synonyms	5-Bromo-2-(benzyloxy)-3-nitropyridine; 3-Nitro-5-bromo-2-(phenylmethoxy)pyridine; 2-Benzyloxy-5-bromo-3-nitropyridine; Pyridine, 5-bromo-2-(phenylmethoxy)-3-nitro-; 1245643-66-6
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-Bromo-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.