Description

4-Amino-5,6-dihydropyridin-2(1H)-one is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyridinone class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• API Synthesis: Employed in the multi-step synthesis of complex target molecules, leveraging its reactive amino and carbonyl functional groups for further derivatization.
• Chemical Biology Probes: Acts as a precursor for designing molecular probes to study biological pathways and enzyme functions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Amino-5,6-dihydropyridin-2(1H)-one
CAS No.	1245643-32-6
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	4-Amino-1,4,5,6-tetrahydropyridin-2(1H)-one; 4-Amino-5,6-dihydro-2(1H)-pyridinone; 4-Amino-2-oxo-1,4,5,6-tetrahydropyridine; 4-Amino-1,2,5,6-tetrahydropyridin-2-one; 4-Amino-2-pyridone, 5,6-dihydro-; 4-Aminodihydropyridinone; DHP derivative 4-NH2
EINECS	Contact for details

Quality Control

Our 4-Amino-5,6-dihydropyridin-2(1H)-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.